{"id":371,"date":"2021-02-26T20:44:46","date_gmt":"2021-02-26T12:44:46","guid":{"rendered":"https:\/\/project-gcbcoa.ltworkshop.com\/?page_id=371"},"modified":"2021-02-26T20:44:46","modified_gmt":"2021-02-26T12:44:46","slug":"%e5%ba%b7%e5%a4%8d%e5%90%8e%e8%b7%9f%e8%bf%9b","status":"publish","type":"page","link":"https:\/\/project-gcbcoa.ltworkshop.com\/zh-hans\/%e8%ae%a4%e8%af%86%e4%b9%b3%e7%99%8c\/%e5%ba%b7%e5%a4%8d%e5%90%8e%e8%b7%9f%e8%bf%9b\/","title":{"rendered":"\u5eb7\u590d\u540e\u8ddf\u8fdb"},"content":{"rendered":"\n

1. \u5316\u7597\u5f15\u8d77\u7684\u5fc3\u810f\u95ee\u9898<\/p>\n\n\n\n

\u7f8e\u56fd\u5fc3\u810f\u534f\u4f1a\u66fe\u5bf9\u4e73\u764c\u60a3\u8005\u53d1\u51fa\u8b66\u544a\uff0c\u6307\u5316\u7597\u548c\u653e\u5c04\u6027\u6cbb\u7597\u53ef\u80fd\u5bfc\u81f4\u5fc3\u810f\u8870\u7aed\u3001\u5fc3\u808c\u75c5\u548c\u5176\u4ed6\u4e25\u91cd\u5fc3\u810f\u95ee\u9898\uff0c\u66f4\u53ef\u80fd\u5728\u6cbb\u7597\u540e\u6570\u5e74\u624d\u53d1\u751f\uff0c\u4f46\u75c5\u53cb\u4e0d\u5e94\u56e0\u6b64\u800c\u9003\u907f\u6cbb\u7597\uff0c\u534f\u4f1a\u5efa\u8bae\u5316\u7597\u540e\u7684\u4e73\u764c\u60a3\u8005\u53ef\u900f\u8fc7\u5b9a\u671f\u800c\u6301\u4e45\u7684\u5065\u5eb7\u996e\u98df\u6765\u51cf\u5c11\u5fc3\u810f\u75be\u75c5\u98ce\u9669\u3002<\/p>\n\n\n\n

\u53e6\u6709\u7814\u7a76\u62a5\u544a\u4ea6\u6307\uff0c\u67d0\u4e9b\u5316\u7597\u836f\u4f1a\u5bf9\u5fc3\u810f\u5e26\u6765\u4e0d\u826f\u7684\u5f71\u54cd\uff0c\u5305\u62ec\uff1aAnthracyclines\u3001Mitoxantrone\u3001Paclitaxel\u3001Docetaxel\u3001Trastuzumab (Herceptin)\u3001Pertuzumab(Perjeta) \u7b49\u3002\u6545\u6700\u597d\u5728\u5316\u7597\u524d\u5148\u6d4b\u8bd5\u5fc3\u810f\u529f\u80fd\uff0c\u5316\u7597\u671f\u95f4\u4ea6\u8981\u7531\u533b\u751f\u5bc6\u5207\u76d1\u5bdf\u60c5\u51b5\uff0c\u670d\u7528\u91cf\u4ea6\u4e0d\u5e94\u8d85\u51fa\u5efa\u8bae\u7684\u6700\u9ad8\u7d2f\u79ef\u5242\u91cf\u3002<\/p>\n\n\n\n

\u8fd8\u6709\u4e00\u4e2a\u4e73\u764c\u5e38\u7528\u7684\u5316\u7597\u836f\u7269\uff1aCyclophosphamide (Endoxan\u00ae\u764c\u5f97\u661f)\uff0c\u5728\u9ad8\u5242\u91cf(>100mg\/kg\/day)\u7684\u60c5\u51b5\u4e0b\uff0c\u6709\u53ef\u80fd\u4f1a\u9020\u6210\u6025\u6027\u5fc3\u808c\u75c5\u53d8\u5e76\u5bfc\u81f4\u5fc3\u8870\u7aed\uff0c\u53ea\u662f\u8fd9\u6837\u7684\u5242\u91cf\u901a\u5e38\u7528\u4e8e\u8840\u6db2\u80bf\u7624\u6216\u662f\u9aa8\u9ad3\u79fb\uff0c\u4e73\u764c\u6240\u9700\u7684\u6cbb\u7597\u5242\u91cf\u5219\u8fdc\u4f4e\u4e8e\u6b64\u3002<\/p>\n\n\n\n

2. \u7126\u8651\u3001\u5fe7\u90c1\u3001\u75b2\u5026\u3001\u75bc\u75db<\/p>\n\n\n\n

\u5316\u7597\u671f\u95f4\uff0c\u867d\u7136\u836f\u7269\u4e0d\u4f1a\u5f71\u54cd\u60c5\u7eea\uff0c\u4f46\u59cb\u7ec8\u5316\u7597\u662f\u4e00\u4ef6\u4ee4\u4eba\u6709\u538b\u529b\u7684\u4e8b\uff0c\u60a3\u8005\u51fa\u73b0\u60ca\u6050\u3001\u5931\u63a7\u3001\u54ed\u6ce3\u7b49\u60c5\u7eea\u95ee\u9898\u90fd\u662f\u5f88\u6b63\u5e38\u7684\uff0c\u81f3\u4e8e\u662f\u5426\u9700\u5bfb\u6c42\u5fc3\u7406\u533b\u751f\u534f\u52a9\uff0c\u5219\u987b\u89c6\u4e4e\u75c5\u53cb\u7684\u4e2a\u522b\u60c5\u51b5\u3002\u5176\u5b9e\u5bb6\u4eba\u3001\u540c\u8def\u4eba\u3001\u793e\u5de5\u90fd\u53ef\u4e3a\u75c5\u53cb\u63d0\u4f9b\u60c5\u7eea\u758f\u5bfc\u652f\u63f4\uff0c\u4f46\u82e5\u51fa\u73b0\u81ea\u6740\u503e\u5411\uff0c\u5f53\u7136\u8981\u5411\u5fc3\u7406\u533b\u751f\u6c42\u52a9\u3002<\/p>\n\n\n\n

3. \u8ba4\u77e5\u529f\u80fd<\/p>\n\n\n\n

\u5c0f\u90e8\u5206\u4e73\u764c\u60a3\u8005\u5728\u5316\u7597\u540e\u51fa\u73b0\u8ba4\u77e5\u529f\u80fd\u4e0b\u964d\uff0c\u5373\u300c\u5316\u7597\u8111\u300d(Chemo Brain)\u7684\u95ee\u9898\u3002\u4e3b\u8981\u8868\u73b0\u4e3a\u5b66\u4e60\u80fd\u529b\u4e0b\u964d\u3001\u8bb0\u5fc6\u529b\u635f\u5bb3\u3001\u8bed\u8a00\u969c\u788d\u3001\u6ce8\u610f\u529b\u51cf\u9000\u3001\u6267\u884c\u80fd\u529b\u51cf\u4f4e\u7b49\u3002\u79d1\u5b66\u5bb6\u53d1\u73b0\uff0c\u8fd9\u4e9b\u60c5\u51b5\u662f\u56e0\u6709\u4e9b\u5316\u7597\u836f\u7269\u5728\u6cbb\u7597\u540e\u4ecd\u4f1a\u5f71\u54cd\u8111\u7ec6\u80de\uff0c\u751a\u6216\u8bf1\u53d1\u4e2d\u67a2\u795e\u7ecf\u7cfb\u7edf\u9000\u5316\uff0c\u4ea6\u6709\u53ef\u80fd\u662f\u4e0e\u6cbb\u7597\u76f8\u5173\u7684\u75b2\u52b3\u3001\u5fe7\u90c1\u53ca\u7126\u8651\u6240\u9020\u6210\u3002\u90e8\u5206\u60a3\u8005\u5f88\u5feb\u51fa\u73b0\u8fd9\u79cd\u60c5\u51b5\uff0c\u4f46\u6301\u7eed\u8f83\u77ed\u7684\u65f6\u95f4\uff1b\u6709\u4e9b\u4eba\u5219\u4f1a\u6709\u8f83\u957f\u671f\u7684\u53d8\u5316\uff0c\u60df\u73b0\u65f6\u4ecd\u672a\u786e\u5b9a\u6210\u56e0\u3002<\/p>\n\n\n\n

\u9047\u5230\u6b64\u95ee\u9898\u7684\u75c5\u53cb\uff0c\u53ef\u5c1d\u8bd5\u4ee5\u4e0b\u6d3b\u52a8\u4ee5\u63d0\u5347\u751f\u6d3b\u8d28\u7d20\uff1a<\/p>\n\n\n\n

i. \u7b80\u5355\u8fc7\u751f\u6d3b\uff0c\u522b\u5c1d\u8bd5\u4e00\u6b21\u505a\u592a\u591a\u4e8b\u60c5<\/p>\n\n\n\n

ii. \u8be6\u5217\u6bcf\u5929\u9700\u8981\u505a\u7684\u4e8b\u53ca\u6446\u653e\u4e1c\u897f\u7684\u4f4d\u7f6e<\/p>\n\n\n\n

iii. \u91cd\u590d\u53d9\u8ff0\uff0c\u589e\u52a0\u5370\u8c61<\/p>\n\n\n\n

iv. \u627e\u5b89\u9759\u7684\u5730\u65b9\u4e0e\u4eba\u4ea4\u8c08<\/p>\n\n\n\n

v. \u591a\u5403\u852c\u83dc\u6709\u52a9\u5927\u8111\u5065\u5eb7\uff0c\u8fd8\u8981\u7ecf\u5e38\u8fd0\u52a8\uff0c\u6709\u5145\u8db3\u7684\u4f11\u606f\u548c\u7761\u7720<\/p>\n\n\n\n

vi. \u53ef\u591a\u73a9\u731c\u5b57\u3001\u6570\u72ec\u3001\u62fc\u56fe\u6216\u5b66\u4e60\u65b0\u7684\u8bed\u8a00\uff0c\u4fdd\u6301\u5934\u8111\u7075\u6d3b<\/p>\n\n\n\n

4. \u6dcb\u5df4\u6c34\u80bf<\/p>\n\n\n\n

\u6dcb\u5df4\u7cfb\u7edf\u662f\u8eab\u4f53\u5185\u7684\u6dcb\u5df4\u6db2\u7ecf\u6dcb\u5df4\u7ba1\u9053\u6d41\u52a8\u5230\u5206\u5e03\u5168\u8eab\u7684\u6dcb\u5df4\u7ed3\uff0c\u628a\u6709\u5bb3\u7684\u7ec6\u83cc\u53ca\u75c5\u6bd2\u8fc7\u6ee4\u53ca\u6d88\u706d\uff0c\u4fdd\u62a4\u8eab\u4f53\u514d\u53d7\u611f\u67d3\u3002\u800c\u6dcb\u5df4\u7ed3\u4e3b\u8981\u96c6\u4e2d\u5728\u5173\u8282\u90e8\u4f4d\uff0c\u5982\u814b\u4e0b\u3001\u8179\u80a1\u6c9f\u3001\u8179\u90e8\u3001\u80f8\u90e8\u548c\u9888\u90e8\u5468\u56f4\u3002\u5f53\u6dcb\u5df4\u7cfb\u7edf\u51fa\u73b0\u4e00\u4e9b\u7269\u7406\u6027\u7684\u969c\u788d\uff0c\u79ef\u805a\u7684\u6dcb\u5df4\u6db2\u4f1a\u56e0\u8fc7\u5927\u7684\u6e17\u900f\u538b\u529b\uff0c\u4ece\u6dcb\u5df4\u7ba1\u6d41\u5230\u76ae\u80a4\u5c42\uff0c\u5f62\u6210\u6dcb\u5df4\u6c34\u80bf\u3002<\/p>\n\n\n\n

\u6dcb\u5df4\u6c34\u80bf\u662f\u6162\u6027\u75c5\u75c7\uff0c\u53ef\u5728\u63a5\u53d7\u4e73\u623f\u6cbb\u7597\u540e\u51e0\u4e2a\u6708\u751a\u6216\u51e0\u5e74\u540e\u51fa\u73b0\uff0c\u800c\u4e73\u623f\u814b\u4e0b\u6dcb\u5df4\u7ed3\u5ed3\u6e05\u624b\u672f(Axillary lymph node dissection)\u6216\u653e\u5c04\u6cbb\u7597\u5747\u4f1a\u4ee4\u6dcb\u5df4\u7ed3\u53d7\u635f\uff0c\u4ece\u800c\u963b\u788d\u6dcb\u5df4\u6db2\u6d41\u52a8\u3002\u65e9\u671f\u5f81\u72b6\u6709\uff1a\u4e0a\u81c2\u611f\u89c9\u75bc\u75db\u3001\u4e0a\u80a2\u5916\u89c2\u6709\u5f02\u7b49\u3002\u6dcb\u5df4\u6c34\u80bf\u662f\u65e0\u6cd5\u6839\u6cbb\u7684\uff0c\u4f46\u53ef\u63a7\u5236\u80bf\u80c0\u53ca\u51cf\u4f4e\u60a3\u8702\u7a9d\u7ec4\u7ec7\u708e\u7684\u98ce\u9669\uff0c\u800c\u6539\u5584\u80a2\u4f53\u6d3b\u52a8\u529f\u80fd\u3001\u7269\u7406\u6cbb\u7597\u548c\u6309\u6469\u5f15\u6d41\uff0c\u90fd\u6709\u52a9\u6539\u5584\u4e0d\u9002\u3002<\/p>\n\n\n\n

5. \u9aa8\u8d28\u758f\u677e<\/p>\n\n\n\n

\u4e73\u764c\u60a3\u8005\u6709\u673a\u4f1a\u8981\u8fdb\u884c\u5316\u7597\uff0c\u6709\u90e8\u5206\u75c5\u53cb\u7684\u5375\u5de2\u529f\u80fd\u53ef\u80fd\u4f1a\u56e0\u5316\u7597\u800c\u51fa\u73b0\u9000\u5316\u7684\u73b0\u8c61\u3002\u4ecd\u7136\u6709\u7ecf\u671f\u7684\u5973\u6027\uff0c\u82e5\u4e73\u764c\u80bf\u7624\u8377\u5c14\u8499\u53d7\u4f53\u4e3a\u9633\u6027\uff0c\u4fbf\u53ef\u80fd\u8981\u4f7f\u7528\u6291\u5236\u8377\u5c14\u8499\u5236\u5242\u6216\u662f\u5355\u4e00\u96cc\u6027\u7d20\u63a5\u53d7\u4f53\u6291\u5236\u5242\uff0c\u4f7f\u8111\u4e0b\u5782\u4f53\u65e0\u6cd5\u5206\u6ccc\u6027\u817a\u6fc0\u7d20\uff0c\u8fdb\u4e00\u6b65\u8ba9\u5375\u5de2\u65e0\u6cd5\u5206\u6ccc\u96cc\u6fc0\u7d20\uff0c\u6765\u63a7\u5236\u53ca\u6cbb\u7597\u75c5\u60c5\u3002<\/p>\n\n\n\n

\u65e0\u8bba\u505c\u7ecf\u524d\u540e\uff0c\u4f7f\u7528\u8377\u5c14\u8499\u6291\u5236\u5242\u8fdb\u884c\u6cbb\u7597\u7684\u75c5\u53cb\uff0c\u90fd\u4f1a\u6709\u9aa8\u9abc\u808c\u8089\u9178\u75db\u4e0e\u9aa8\u8d28\u758f\u677e\u7684\u95ee\u9898\uff0c\u6240\u4ee5\u8981\u6ce8\u610f\u9884\u9632\u9aa8\u8d28\u758f\u677e\u3002<\/p>\n\n\n\n

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